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Epicutis Hydrobiome Serum

Epicutis Hydrobiome Serum

$160.00

Product Benefits

  • Balances Microbiome & Strengthens Barrier: This serum is EWG Verified (pending) and designed to improve overall skin health by balancing the microbiome and strengthening the skin barrier with clinically proven actives like TCP and TPNa.
  • Calms Irritation & Targets C. acnes: TCP, a patented TLR2 modulator, calms visible irritation and targets C. acnes, supporting the balance of beneficial flora.
  • Antioxidant Protection: TPNa, a next-generation water-soluble Vitamin E, provides antioxidant protection and further strengthens the skin barrier.
  • Instant & Deep Hydration: Sodium Hyaluronate instantly boosts skin's moisture levels, while Propanediol contributes to skin plumping and anti-microbial benefits.
  • Visibly Clearer, Calmer, and More Resilient Skin: The combined action of its ingredients soothes discomfort, promotes microbiome equilibrium, and reinforces the skin barrier for improved clarity, calmness, and resilience.
Size

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Product Details

The EPICUTIS® Hydrobiome Serum is an EWG Verified (pending) formulation designed to improve overall skin health through balancing the microbiome and strengthening the skin barrier. This advanced formula combines two clinically proven actives — TCP, a patented, TLR2 modulator developed by Signum Biosciences that calms irritation and targets C. acnes and TPNa, a next-generation, form of water-soluble Vitamin E chosen for its antioxidant protection and ability to strengthen the skin barrier.

TCP works harmoniously within the skin’s microbiome, helping to calm visible irritation while supporting the balance of beneficial flora essential for healthy skin. Combined with TPNa's strengthening of the skin barrier, this formulation is ideal for any barrier damage or general maintenance. These ingredients soothe discomfort, promote microbiome equilibrium, and reinforce the skin barrier for visibly clearer, calmer, and more resilient skin.

Lightweight and fast-absorbing, the Hydrobiome Serum delivers a refined, soothing experience that nurtures long-term skin health and balance in your microbiome.

Balancing, Calming + Strengthening Ingredients: 

  • TCP to balance the microbiome + calm inflammation
  • TPNa provides anti-oxidant protection
  • Sodium Hyaluronate to instantly boost skin's moisture level
  • Propanediol for skin plumping + anti-microbial benefits
How To Use

Apply two pumps of serum to clean fingertips. Gently spread it evenly over your face until it is fully absorbed. For your neck and décolleté, use an additional pump. For optimal results, use morning and night.

Ingredients

Key Ingredients:

  • Pentylene Glycol - a plant-derived diol that functions as a humectant and solvent to attract moisture, stabilize emulsions and boost preservative performance in skincare formulations. Its antimicrobial properties and low molecular weight support hydration, texture enhancement and ingredient delivery without irritating sensitive skin.
  • Sodium Hyaluronate - the sodium salt of hyaluronic acid that penetrates deeply to bind moisture, plump skin, and smooth fine lines. It forms a protective, lightweight film to reduce water loss and calm inflammation, making it an essential humectant for dry, sensitive, and aging skin in serums, creams, and masks.
  • Propanediol - a corn-derived humectant and solvent that boosts hydration, smooths texture, and supports the skin barrier with a lightweight, non-sticky feel. It enhances ingredient penetration, improves preservative efficacy, and stabilizes formulations, serving as a sustainable alternative to propylene glycol for all skin types.
  • Glycerin - a powerful natural humectant that draws moisture to the skin, creating a lasting hydration reservoir. It penetrates through aquaporin-3 channels to strengthen the barrier, support cell membrane fluidity, and enhance other ingredients—making it ideal for dry, sensitive, or compromised skin and suitable for all skin types.

INCI Ingredients:

Water, Propanediol, Pentylene Glycol, Glycerin, Disodium Tetramethylhexadecenylcysteine Formylprolinate, Sodium Tocopheryl Phosphate, Sodium Hyaluronate, Sodium Phytate, Carbomer, Potassium Hydroxide

Shipping & returns

Domestic Shipping Policy
We offer free shipping on all orders over $50 within the contiguous United States. Orders under $50 will incur a flat shipping fee of $4.90.
Most U.S. orders are delivered within 3–7 business days from the ship date, unless there are carrier-related delays. Orders shipped to Hawaii and Alaska may take longer to arrive.
Need it faster? Select Express Shipping at checkout! We offer free Express shipping on orders over $250, with delivery in 2–3 business days. A flat rate shipping fee of $9.90 applies to orders below $250.

Domestic Returns Policy
We want you to feel confident shopping with DermSkinLab. If you are not completely satisfied with your purchase, you may return it within 30 days.
To qualify for a return, products must be unused, unopened, and in their original condition.
Please contact us first at customercare@dermskinlab.com. Be sure to include your name and order number, and our team will get back to you with return instructions.

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Clinically Proven

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